misfortune /ˈmisfɔ:tʃən/ n. ［u］&  ［c］不幸，厄运，逆境；灾难，灾祸，不幸事故: domestic misfortune 家庭的不幸；invite misfortune 招惹不幸； suffer some misfortune 遭受某种不幸 Misfortunes never come single.［谚］祸不单行。［考句］He believed that the greatest of his  misfortunes was that he’d never had a college education.他认为他最大的不幸是从未受过高等教育。